Objective. To determine the effectiveness of intramuscular progesterone compared to vaginal application in the prevention of asymptomatic preterm birth (PTB) in randomized clinical trials. Materials and Methods. A systematic search of electronic databases (Embase, PubMed and Scopus) was performed. Randomized clinical trials comparing vaginal and Intramuscular progesterone (17-OHPC) in pregnant women at high risk of PTB. Additionally, bias and certainty assessment were performed. Results. Six clinical trials with a total of 1,408 randomized patients were included. The reported incidence of PTB < 37 weeks ranged from 10.9% to 43.9% for vaginal progesterone, and 14.0% to 38% for 17-OHPC. At the time of meta-analysis, patients receiving 17-OHPC was associated with a lower incidence of PTB < 28 weeks than vaginal use (Risk Difference 0.14; CI 0.01-0.29; I2 = 83.9%; T2 = 0.02) with no signific...

The COVID-19 pandemic has exposed the general population to constant stressful and traumatic situations. This, added to the necessary and constant dissemination of preventive measures for COVID-19 infection, can generate an increase in the prevalence of Obsessive-Compulsive (OC) symptoms. Thus, this research aimed to evaluate the prevalence of OC symptoms and explore associated factors in young adults in Peru, the country with the highest COVID-19 death rate in the world. In this analytical cross-sectional study, an online survey distributed through social networks was used. OC symptomatology during the last week was measured by the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). Possible Generalized Anxiety Disorder (GAD) and Major Depressive Disorder (MDD) were evaluated with the General Anxiety Disorder 7-items (GAD-7) and Patient Health Questionnaire-9 (PHQ-9), respectively. 1243 you...

Antecedentes: El cáncer de próstata localizado (T1-3N0M0) tiene opciones terapéuticas como la prostatectomía radical (PR), la radioterapia de haz externo (EBRT) y la braquiterapia (BT). Sin embargo, la evidencia de los resultados de estos tratamientos es limitada y no se han realizado estudios que comparen el Falla Bioquímica (FB) y la toxicidad asociada al tratamiento quirúrgico y a la EBRT + Braquiterapia de alta dosis (HDBT) en la región. Material y Métodos: Estudio de cohorte retrospectivo, se revisaron las historias clínicas de los pacientes diagnosticados con cáncer de próstata localizado entre 2014 y 2018 en uno de los principales centros privados de neoplasias de Lima, Perú; se utilizó la regresión de Cox tanto para el resultado de BF como para el resultado de toxicidad grado 2, calculando el HR con IC 95%. Resultados: De 549 pacientes, el 76,3% (419) recibió RP co...

Objective: To analyze the variation in attendance and diagnoses after the national vaccination campaign against COVID-19 in the pediatric emergency department. The study: Analytical retrospective cross-sectional study. Pediatric emergency department visits were compared between epidemiological weeks 1 and 52 of the years 2020 and 2021, analyzing sociodemographic characteristics, condition and diagnosis. Chi-square was used for bivariate analysis. Findings: A 77.8% increase was found in the number of attentions during the year 2021 compared to 2020. There was a 4% increase in infectious diseases and a 9.2% increase in respiratory diseases. In addition, a decrease of 8.7% was observed in gastrointestinal diseases. Conclusion: The results indicate that after the start of the national vaccination campaign, there was a significant increase in the number of patients compared to 2020, mainly fo...

Objective: To analyze the variation in attendance and diagnoses after the national vaccination campaign against COVID-19 in the pediatric emergency department. The study: Analytical retrospective cross-sectional study. Pediatric emergency department visits were compared between epidemiological weeks 1 and 52 of the years 2020 and 2021, analyzing sociodemographic characteristics, condition and diagnosis. Chi-square was used for bivariate analysis. Findings: A 77.8% increase was found in the number of attentions during the year 2021 compared to 2020. There was a 4% increase in infectious diseases and a 9.2% increase in respiratory diseases. In addition, a decrease of 8.7% was observed in gastrointestinal diseases. Conclusion: The results indicate that after the start of the national vaccination campaign, there was a significant increase in the number of patients compared to 2020, mainly fo...

Introducción: Se identificó las infecciones respiratorias agudas (IRA) como un problema de salud principal según el ASIS Lima Sur 2018. Dentro de las IRA, la neumonía presenta el mayor impacto en menores de 5 años, afectando tanto la salud como el desarrollo de la población. Diversos estudios resaltan la escasez de adecuados conocimientos, actitudes y prácticas para hacer frente a la neumonía. El objetivo del estudio fue identificar el impacto de brindar educación comunitaria acerca de la “Neumonía y signos de alarma” y “Medidas Higiénico dietéticas”. Se ejecutó el proyecto en el A.H Pacifico de Villa - Chorrillos entre agosto y noviembre de 2020. Materiales y métodos: Se realizó un estudio de diseño cuasi experimental descriptivo de corte transversal, y para ello se utilizó la herramienta del marco lógico. La intervención consistió en difundir material educat...