Objective: To determine the blood levels of two oxidative stress biomarkers among native women exposed to wood smoke living at high altitude (3,850 m a.s.l.). Malondialdehyde (MDA) levels and carboxyhemoglobin (COHb) percentage in venous blood, which is also a cellular hypoxia biomarker, were analyzed. Materials and methods: A descriptive case-series study conducted in 74 women between 14 and 55 years of age exposed to wood smoke and coming from the rural area of the Copacabana Municipality (La Paz, Bolivia) at 3,850 m a.s.l. Screening was carried out through a survey and a complete physical examination. MDA levels and COHb percentage in venous blood were determined, and the demographic variables and transcutaneous oxygen saturation were measured. A descriptive statistical analysis was performed and measures of central tendency were calculated using IBM SPSS Statistics Version 18. Result...