The objective of the study was to determine the relationship that exists between the epidemiological characteristics and the level of severity of acute cholecystitis in emergency patients Hospital Regional de Loreto Iquitos 2022, the method was quantitative, non-experimental, descriptive, correlational cross-sectional design. The population and sample were 130 medical records of patients with acute cholecystitis. The technique was the documentary review and the instruments, Epidemiological data sheet of patients with acute cholecystitis and the record sheet for identifying the level of severity of acute cholecystitis. For data processing and analysis, the statistical package SPSS version 24.0 and the non-parametric inferential test of free distribution Chi Square (X2) with a significance level of α 0.05 were used. The results were: 43.1% were between 18 and 35 years old, 73.8% were fema...