The improvement of heat transfer is the focus of this paper’s innovative theoretical ternary hybridity nanofluid (HNF) prototype. In this examination, blood is employed as the conventional liquid, and the tri-hybrid nanomolecules Au, Ag, and TiO2 are submerged in it. The extension has been made in the conventional Tiwari and Das hybrid nanofluid model to transform it for the case of a trihybrid nanofluid. By consuming resemblance variables and the Keller box methodology (KBM) to resolve the ordinary differential equations (ODEs) resulting from the conversion of the liquid flowing and temperature formulas. The results are graphed, and it is shown that the trihybridity nanofluid (THNF) has greater thermal conductance than the HNF. The heat transference rate increases in the situation of an augmentation in thermal conduction and radiation effect which helps remove the toxic plaque from th...