The analytical method validation is an integral part of the quality control system, since it gives reliability to the analytical results obtained in a laboratory, to ensure that a drug comply established equality parameters. We present the validation of an analytical method for quantification of 2 mg Risperidone tablets, using the technique of spectrophotometry UV / VIS proposed by the authors G. Alagumanivasagam, A. Anton Smith, Department of Pharmacy, Annamalai University in India.For the analysis of 2 mg Risperidone tablets from three pharmaceutical laboratories (Farmindustria, Marfan and Medrock) methanol was used as solvent and was measured at a wavelength of maximum absorbance of 278 nm.The samples were subjected to acid degradation, alkaline oxidation and thermolysis, obtaining interference less than 2%. The linearity test method showed a correlation coefficient of 0.9998910. For ...