There is a consensus that the long-term consequences of ovarian deprivation can be prevented or reduced by trabecular bone therapy in one out of two cases resulting in lifetime risks of osteoporotic fractures. Hormone replacement therapy (HRT) prevented this loss of bone and decreases the incidence of fractures. a minimum of 5 years of treatment is recommended to achieve significant benefits. Epidemiologic evidence is accumulating in that postmenopausal estrogen therapy reduces the risk of cardiovascular disease and stroke by about 30% and 70%, even in the presence of established risk factors. Given the frequency of cardiovascular disease, it becomes probably one of the original advantages of using hormone replacement therapy in the next decade. Concerns about the long-term safety of HRT have focused on breast and endometrial cancer. The increased risk of endometrial cancer associated wi...

There is a consensus that the long-term consequences of ovarian deprivation can be prevented or reduced by trabecular bone therapy in one out of two cases resulting in lifetime risks of osteoporotic fractures. Hormone replacement therapy (HRT) prevented this loss of bone and decreases the incidence of fractures. a minimum of 5 years of treatment is recommended to achieve significant benefits. Epidemiologic evidence is accumulating in that postmenopausal estrogen therapy reduces the risk of cardiovascular disease and stroke by about 30% and 70%, even in the presence of established risk factors. Given the frequency of cardiovascular disease, it becomes probably one of the original advantages of using hormone replacement therapy in the next decade. Concerns about the long-term safety of HRT have focused on breast and endometrial cancer. The increased risk of endometrial cancer associated wi...