This paper is concerned with traveling wave solutions for a delayed reaction-diffusion SVIR epidemic model that includes both general incidence function and imperfect vaccination. In the model, the spread of infection in space is explicitly taken into account by using a heterogeneous environment; it takes into consideration the delay in immune response and inefficiency in vaccinations. The analysis carried out below shows that the basic reproduction number Ro will be a critical value for determining the existence of traveling waves. More precisely, when Ro > 1 there exists a minimal wave speed ρ* > 0 such that the system admits nontrivial traveling wave solutions for ρ ≥ ρ* whereas no such solutions exist for ρ < ρ*. On the other hand, if Ro ≤ 1, there are no traveling wave solutions. The introduction of delays and imperfect vaccination adds richness and complexity to t...