We report two cases of well differentiated thyroid carcinoma (DTC) in two girls who showed their first symptoms at 4 years 6 months and 7 years 2 months. Both underwent total thyroidectomy and removal of metastatic lymph nodes. In the first case pathology informed a mixed DTC (papillar/follicular). In the first case we discuss the difficulties that may arise due to the unspecified signs and symptoms that led to an initial diagnosis of goiter and thyroiditis. We emphasize the importance of age, sex, the presence of cervical adenopathy and associated hoarness in order to establish the diagnosis of DTC. In the second case we point out the diagnostic importance of the progressive growth of the cold thyroid nodule. We review the different surgical approaches of resection supporting the advantages of the total over the subtotal thyroidectomy we had done on our patients. We analyze the ...