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Guidance for assessment of the inflammation etiologic criterion for the GLIM diagnosis of malnutrition: A modified Delphi approach

Publicado por
Cederholm, Tommy, Jensen, Gordon L., Ballesteros-Pomar, Maria D., Blaauw, Renee, Correia, M. Isabel T.D., Cuerda, Cristina, Evans, David C., Fukushima, Ryoji, Ochoa Gautier, Juan Bernardo, Gonzalez, M. Cristina, Van Gossum, Andre, Gramlich, Leah, Hartono, Joseph, Heymsfield, Steven B., Jager-Wittenaar, Harriët, Jayatissa, Renuka, Keller, Heather, Malone, Ainsley, Manzanares, William, McMahon, M. Molly, Mendez, Yolanda, Mogensen, Kris M., Mori, Naoharu, Muscaritoli, Maurizio, Nogales, Guillermo Contreras, Nyulasi, Ibolya, Phillips, Wendy, Pirlich, Matthias, Pisprasert, Veeradej, Rothenberg, Elisabet, de van der Schueren, Marian, Shi, Han Ping, Steiber, Alison, Winkler, Marion F., Barazzoni, Rocco, Compher, Charlene

Publicado 2024

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Background & aims: The Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) criteria, with diagnosis confirmed by fulfillment of any combination of at least one phenotypic and at least one etiologic criterion. The original GLIM description provided limited guidance regarding assessment of inflammation and this has been a factor impeding further implementation of the GLIM criteria. We now seek to provide practical guidance for assessment of inflammation in support of the etiologic criterion for inflammation. Methods: A GLIM-constituted working group with 36 participants developed consensus-based guidance through a modified-Delphi review. A multi-round review and...