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Assessing the impact of a multidimensional approach and an 8-component bundle in reducing incidences of ventilator-associated pneumonia across 35 countries in Latin America, Asia,...

Publicado por
Rosenthal, Victor Daniel, Jin, Zhilin, Yin, Ruijie, Sahu, Suneeta, Rajhans, Prasad, Kharbanda, Mohit, Nair, Pravin K., Mishra, Shakti Bedanta, Chawla, Rajesh, Arjun, Rajalakshmi, Sandhu, Kavita, Rodrigues, Camilla, Dongol, Reshma, Myatra, Sheila Nainan, Mohd-Basri, Mat Nor, Chian-Wern, Tai, Bhakta, Arpita, Bat-Erdene, Ider, Acharya, Subhash P., Alvarez, Gustavo Andres, Moreno, Lina Alejandra Aguilar, Gomez, Katherine, da Jimenez-Alvarez, Luisa Fernanda, Henao-Rodas, Claudia Milena, Valderrama-Beltran, Sandra Liliana, Zuniga-Chavarria, Maria Adelia, Aguirre-Avalos, Guadalupe, Hernandez-Chena, Blanca Estela, Sassoe-Gonzalez, Alejandro, Aleman-Bocanegra, Mary Cruz, Villegas-Mota, Maria Isabel, De Moros, Daisy Aguilar, Castaneda-Sabogal, Alex, Carreazo, Nilton Yhuri, Alkhawaja, Safaa, Agha, Hala Mounir, El-Kholy, Amani, Abdellatif-Daboor, Mohammad, Dursun, Oguz, Okulu, Emel, Havan, Merve, Yildizdas, Dincer, Deniz, Suna Secil Ozturk, Guclu, Ertugrul, Hlinkova, Sona, Ikram, Aamer, Tao, Lili, Omar, Abeer Aly, Elahi, Naheed, Memish, Ziad A., Petrov, Michael M., Raka, Lul, Janc, Jarosław, Horhat-Florin, George, Medeiros, Eduardo Alexandrino, Salgado, Estuardo, Dueñas, Lourdes, Coloma, Monica, Perez, Valentina, Brown, Eric Christopher

Publicado 2024

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Background: Ventilator associated pneumonia (VAP) occurring in the intensive care unit (ICU) are common, costly, and potentially lethal. Methods: We implemented a multidimensional approach and an 8-component bundle in 374 ICUs across 35 low and middle-income countries (LMICs) from Latin-America, Asia, Eastern-Europe, and the Middle-East, to reduce VAP rates in ICUs. The VAP rate per 1000 mechanical ventilator (MV)-days was measured at baseline and during intervention at the 2nd month, 3rd month, 4–15 month, 16–27 month, and 28–39 month periods. Results: 174,987 patients, during 1,201,592 patient-days, used 463,592 MV-days. VAP per 1000 MV-days rates decreased from 28.46 at baseline to 17.58 at the 2nd month (RR = 0.61; 95% CI = 0.58–0.65; P < 0.001); 13.97 at the 3rd month (RR = 0.49; 95% CI = 0.46–0.52; P < 0.001); 14.44 at the 4–15 month (RR = 0.51; 95% CI = 0.48–0.53; P ...