El presente trabajo de investigación tuvo como objetivo extraer con CO2 supercrítico el aceite de semillas de Vitis vinífera de la variedad Quebranta de Ica, aprovechando los residuos (orujo) generados del proceso de elaboración de pisco, y realizar su caracterización fisicoquímica y determinar su actividad antioxidante. Las semillas fueron secadas hasta alcanzar 6 – 7 % de humedad. Se realizó la extracción del aceite por el método convencional (soxhlet) con hexano y con el equipo extractor multisolventes utilizando CO2 supercrítico. Para optimizar el rendimiento de la extracción del aceite con CO2 supercrítico se utilizó el método superficie respuesta, mediante el diseño central compuesto sugeridos por el software Minitab versión 17. Se determinaron las características físicas del aceite (índice de refracción y densidad), químicas (índice de peróxidos, índice d...

The extraction yield of Quebranta grape seed oil was optimized with the response surface method. Three factors were considered: pressure (Pbar), temperature (T) and CO2 flow (F). The response variables were the oil yield, peroxide value (POV) and anisidine. The seed was characterized, and the particle size was established for the oil extraction. The extractions were executed according to the RSM design and the oil yield, POV and anisidine were calculated. The composition of fatty acids was determined by gas chromatography and the antioxidant activity by reduction of the 1,1-diphenyl-2-picrylhydro-radical (DPPH) of the optimized oil obtained with CO2 and that extracted with hexane (control). The Pbar, T and F had significant effect on the oil yield, but did not have significant effect on the POV and anisidine. These results were promising to increase added value of the seed and pisco prod...