This research paper entitled "Evaluation of the implementation of five doses of efficient microorganisms for the control of Pythium sp. and Fusarium sp. in the cultivation of lettuce (Lactuca sativa) variety Lamas Great Lakes 659 - San Martin ", was to assess and analyze the effect of the ME, and to determine the most appropriate dose of M.E Pitium control and sp Fusaium sp. We used the statistical design of randomized complete block design with four treatments and five blocks for a total of twenty experimental units. The results obtained indicate that all the treatments based on the application of different doses of efficient microorganisms, interacted in a synergistic and efficient manner and demonstrated their contribution in improving soil quality, improving crop growth and structural determinants were Pitium controlling Fusarium sp and sp., and increase photosynthetic processes and ...