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tesis de maestría
Publicado 2020
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ABSTRACT Objectives: Ovarian germ cell tumors (OGCT) represent about 4.1% of the pediatric neoplasms at the Instituto Nacional De Enfermedades Neoplasicas (INEN). The aim is our study is to determine the Disease-free survival (DFS) and overall survival (OS) in girls with OGCT at the INEN attended between January 2008 and December 2015. Methods: This is a retrospective cohort study. Thirty-three patients with OGCT under 15 years of age were seen in the study period; eight of them were excluded because inclusion criteria were not met. Patients received chemotherapy with bleomycin 15mg/m2 and cisplatin 100mg/m2 on day 1, and etoposide 150 mg/m2 on days 1 to 3. The OS and DFS were evaluated with the Kaplan-Meier method. Results: Between 2008 and 2015, 33 girls have been treated. Mean age was 11 years (range 5 to 14 years). The most frequent symptoms were abdominal pain and tumor in 81% and 8...