Rangeliosis is an extravascular hemolytic disease caused by the piroplasm Rangelia vitalii. This protozoan is transmitted by ticks of the species Amblyomma aureolatum and infects erythrocytes, endothelial cells, and leukocytes, leading to a variety of clinical signs such as anemia, thrombocytopenia, splenomegaly, hepatomegaly, jaundice, and bleeding from the nose, oral cavity, and ear tips. This study aims to report a case of rangeliosis in a domestic dog in southern Brazil. A female, adult, mixed-breed dog from a rural area was admitted to a Veterinary Hospital. Clinical examination revealed necrosis of the ear tips with active bleeding and abdominal hematomas. After a few days, the patient also developed jaundice, hematuria, bilirubinuria, subconjunctival hemorrhage, and epistaxis. Hematological analysis indicated anemia and thrombocytopenia, while biochemical tests revealed elevated s...