1. Endocrine - clinical study, laboratory and testicular histology in five patients with male hypogonadism is made . Two . Testicular biopsy is a simple and safe procedure , which should be included routinely in every patient with symptoms or siqnos of hipoqonadismo . Three . This testicular biopsy allows us not only to confirm the clinical diagnosis hypogonadal , but now, while the histolóqíco diagnosis, prognosis and guides evaluates rational therapeutics . April . Thanks to this temperament biopsy has allowed us to identify two patients pre - pubertal testis, Del Castillo syndrome and one case of testicular atrophy probably other conditions had been labeled with the generic term of hypogonadism . May . Also consider that the study of sex chromatin should be systematically performed in every patient with testicular endocrinopathy considering new genetic concepts. 6. In our cases the ...