ABSTRAC The impact of the pollution of the waters of the rio Itaya has been investigated by port activities that are generated in the puerto Masusa - Iquitos. A holistic approach, mixing the pre-experimental design (pollution of the waters of the rio Itaya), with transverse description (port activities) and comparative research (environmental impact) was used for the development of research. For this purpose, determined the contamination of the waters of the Itaya River on the shores of puerto Masusa, comparing the results of the physicochemical and microbiological analysis of the standard (the Amazon River behind port Masusa samples) versus the results of sampling (100 metres above the harbour - Harbour - 100 metres down the port). The sampling was carried out for two months (September and November 2011). It has been concluded that there is no significant difference in indicators: pH, o...

Chuquiraga weberbaueri “amaro” (Asteraceae) is a plant species popularly used for the treatment of animal fasciolosis in Peru. However, biological and chemical studies of this species remain scarce. Hence, the objective of the present study was to evaluate the anthelmintic effect of the hydroethanolic and aqueous extracts of C. weberbaueri leaves on Fasciola hepatica, through a controlled and a therapeutic efficacy test in artificially infected sheep. In addition, the chemical composition of the extracts was evaluated using phytochemical screening and analysis by UHPLC-MS/MS. Among the evaluated extracts, the aqueous extract proved to be the most efficient and of low toxicity against F. hepatica, inhibiting about 70% of its oviposition, using a 100 mg/kg dose. The chemical study showed that the major constituents were phenolic derivatives, such as chlorogenic acid and ethyl caffeate,...