The clinical and histopathological aspects as well as the immunohistochemical expression of ocular squamous cell carcinoma (CCEO) were evaluated in 24 cows with ocular and periorbital neoplasms in the department of Nariño, Colombia. The variables were breed, sex, age, location, and stage of the carcinoma. Immunoexpression of p53 and CK19 was determined. There were 15 Holstein, 3 Normado, 3 Simhol, 2 Creole and one Montbéliarde cows and were classified according to age in <3 years (4%), 4-7 years (64%) and >8 years (32%). The carcinoma developed in the nictitating membrane (n=13), sclerocorneal limbus (7), lower eyelid (2), cornea (1) and in the conjunctiva (1). Ten cows presented a hypopigmented periorbital area. Small whitish gray plaques were observed on the third eyelid and cornea, irregular nodules, and cauliflower-shaped sessile warts in the limbus corneal region and eyelids...

The clinical and histopathological aspects as well as the immunohistochemical expression of ocular squamous cell carcinoma (CCEO) were evaluated in 24 cows with ocular and periorbital neoplasms in the department of Nariño, Colombia. The variables were breed, sex, age, location, and stage of the carcinoma. Immunoexpression of p53 and CK19 was determined. There were 15 Holstein, 3 Normado, 3 Simhol, 2 Creole and one Montbéliarde cows and were classified according to age in <3 years (4%), 4-7 years (64%) and >8 years (32%). The carcinoma developed in the nictitating membrane (n=13), sclerocorneal limbus (7), lower eyelid (2), cornea (1) and in the conjunctiva (1). Ten cows presented a hypopigmented periorbital area. Small whitish gray plaques were observed on the third eyelid and cornea, irregular nodules, and cauliflower-shaped sessile warts in the limbus corneal region and eyelids...