Objective: To determine whether personal and institutional factors are associated with the quality of the nursing notes register in hospitalized patients at the National Institute of Neoplastic Diseases. Methodology: A quantitative, basic, descriptive-correlational, non-experimental, cross-sectional study. The population consisted of a total of 129 nursing professionals working in the hospitalization area who prepared nursing notes. Two instruments were used to evaluate the personal and institutional factors and the quality of the nursing notes register, which was validated by expert judgment and with a reliability of Cronbach's alpha 0.8 and KR of 0.86. The results obtained show a moderate correlation (0.695) between the personal and institutional factors and the quality of nursing notes. Likewise, the personal and institutional factors and the content of nursing notes have a moderate c...