Objective. To determine the relationship between the workplace environment and the onset of burnout syndrome in a group of workers from higher education institutes. Methods. Observational, descriptive, cross-sectional research with a correlational descriptive non-experimental design, for data collection two Likert-type scales were used: Palma workplace environment scale and Maslach burnout inventory. The sample consisted of 51 workers, who were selected through a non-probability convenience sampling. Results. A favorable work environment was evidenced in 49 % (25) and unfavorable in 3.9 % (2); 39.2 % (20) experienced the burnout syndrome as medium and 29.4 % (15) as low. The existence of a weak negative correlation between workplace environment and burnout syndrome was found (Rho = -0.377; p = 0.006); weak and significant negative correlation between workplace environment and the exhaust...