Objective: To determine whether pre-conception initiation of antiretroviral (ARV) therapy compared to pregnancy ARV initiation is a risk factor for adverse neonatal outcomes in women more than 18 years old in Belen Hospital in Trujillo (BHT). Material and Methods: This is an analytical observational study performed in a retrospective cohort. Sample size was 168 pregnant women diagnosed with HIV infection and receiving antiretroviral (ARV) therapy, who were divided in two groups: 84 women who started ARV prior to conception and 84 who started ARV after conception. The analysis was performed using the Chi-square test and relative risk (RR) was calculated, with 95% confidence intervals (CI) and 5% significance. Results: The rate of adverse neonatal outcomes was 48.8% in women starting ARV after conception and 21.4% in those who started ARV after conception, and this difference was significa...

Objetivo: Determinar si el inicio de TAR preconcepción es factor de riesgo de resultados adversos neonatales comparado con el inicio de TAR durante la gestación en el tratamiento de VIH en mayores de 18 años en Hospital Belén de Trujillo. Material y métodos: Estudio observacional, retrospectivo y analítico. El tamaño muestral estuvo conformado por 168 gestantes con diagnóstico de VIH en tratamiento con TARGA, divididos en dos grupos 84 gestantes que inician TARGA antes de la gestación y 84 gestantes que inician TARGA durante la gestación. Para el anlisis se utilizo el paquete estadístico IBM SPSS Statistics 27, además de la prueba Chi-cuadrado y el cálculo del riesgo relativo utilizando intervalos de confianza del 95 y significancia estadística del 5%. Resultados: Los resultados evidenciaron que el estado civil (p=0.02), el tipo de TAR (p=0.009) y la carga viral (p=0.000) s...

Objective: To determine whether pre-conception initiation of antiretroviral (ARV) therapy compared to pregnancy ARV initiation is a risk factor for adverse neonatal outcomes in women more than 18 years old in Belen Hospital in Trujillo (BHT). Material and Methods: This is an analytical observational study performed in a retrospective cohort. Sample size was 168 pregnant women diagnosed with HIV infection and receiving antiretroviral (ARV) therapy, who were divided in two groups: 84 women who started ARV prior to conception and 84 who started ARV after conception. The analysis was performed using the Chi-square test and relative risk (RR) was calculated, with 95% confidence intervals (CI) and 5% significance. Results: The rate of adverse neonatal outcomes was 48.8% in women starting ARV after conception and 21.4% in those who started ARV after conception, and this difference was significa...