Objective. To determine the satisfaction of first-level students with their preparation prior to entering the Medicine career at the Technical University of Manabí. Materials and methods. A cross-sectional descriptive study was carried out. A questionnaire validated by expert criteria, with options questions and an open question, was applied to 111 students who were studying the first level of the Medicine career during the period October 2017 to February 2018 and thus know how they valued their previous preparation. at the beginning of their university studies and the leveling semester. In addition, the route of entry and the behavior of failure in that period in the different subjects were analyzed, data that were summarized by using absolute numbers and percentages. Results. 44.1% of the students were male and 62 (55.9%) female, of which the average age was 18 years, 84.8% took entra...