Mujer de 18 años que ingresó al hospital por presentar dolor torácico y disnea de esfuerzos en los últimos nueve meses, más hemoptisis recurrente. Los estudios de imagen revelaron una masa en el mediastino anterior superior. Después de la resección quirúrgica, la histopatología demostró varios tejidos epiteliales y cartilaginosos compatible con teratoma quístico maduro.

An 18 year-old woman entered to the hospital because of thoracic pain and dyspnea on exertion in the last nine months, and recurrent hemoptysis. The image studies revealed a mass in the anterior-superior mediastinum. After surgical resection, histopathology showed several epithelial and cartilaginous tissues compatible with mature cystic teratoma.

Objetive: To describe the atypical histopathologic presentation in bone marrow of multiple myeloma. Case Report: We present the case of a 75-year-old male who manifested low back pain of variable intensity associated with decreased urinary flow, for which he went to the emergency room. On physical examination, vital functions were within normal parameters with generalized decrease in adipose tissue and earthy pallor, the rest of the examination being non-contributory. Bone marrow studies showed 13% of plasma cells with tetranucleated neoplastic cells with 1 and 2 nucleoli, basophilic cytoplasm with presence of vacuoles, which was corroborated in flow cytometry with pathological phenotype in relation to plasma cell neoplasia. The patient receives a therapeutic regimen with cyclophosphamide, dexamethasone and thalidomide. Conclusion: Tetranucleated presentation is a rare histopathologic va...