The objective was to identify stressors in the nursing professionals who work in critical areas of Hospital III in Essalud Puno (Peru). The type of research was descriptive cross-sectional comparative where 45 professionals participated. The instrument applied was the Nursing Stress Scale (NSS) that measures stressful situations in the nursing professional. The results indicate that the factors appear in the physical, psychological and social environment. The most affected was the physical environment, considering the workload at 28.9%. In the psychological environment, lack of support was observed in 28.9%, uncertainty in treatment with 24.4%, insufficient preparation in 17.8%, and death suffering in 16.7%. In the social environment the problems with the doctor is 28% and with other members (nurse or others) 17.8%. Comparing the critical areas in the Essalud III hospital, there are freq...