Aníbal Salas, Carlos Battilana Life in the species evolution when migrating from water to earth developed various adaptative mechanisms for salt regulation. The most important is the currently known yuxtaglomerular system. Diverse pathophysiologic mechanisms are implicated in arterial hypertensionpathogenesis, including enzymatic interaction between WNK1 and SGK1 enzymes, yuxtaglomerular apparatus imbalance, angiotensin II overexcitability, pressure natriuresis, genetic factors recently studied like 11 ß-hydroxysteroid dehydrogenase enzyme gen mutation, aberrant tubular glomerular balance in relation to salt intake, and nephronal subdonor theory. Finally, the close relationship between the metabolic syndrome and arterial hypertension has opened a new horizon on arterial hypertension diagnosis and treatment. All these mechanisms have led to diverse clinical expressions, determining the ...

Aníbal Salas, Carlos Battilana Life in the species evolution when migrating from water to earth developed various adaptative mechanisms for salt regulation. The most important is the currently known yuxtaglomerular system. Diverse pathophysiologic mechanisms are implicated in arterial hypertensionpathogenesis, including enzymatic interaction between WNK1 and SGK1 enzymes, yuxtaglomerular apparatus imbalance, angiotensin II overexcitability, pressure natriuresis, genetic factors recently studied like 11 ß-hydroxysteroid dehydrogenase enzyme gen mutation, aberrant tubular glomerular balance in relation to salt intake, and nephronal subdonor theory. Finally, the close relationship between the metabolic syndrome and arterial hypertension has opened a new horizon on arterial hypertension diagnosis and treatment. All these mechanisms have led to diverse clinical expressions, determining the ...

Twentyfive patients with cardiomyopathy coming from different regions of Peru have been studied the majority (22) at the Hospital Dos de Mayo in the city of Lima. Twentythree were males and two females, and their ages were between 13 and 65 years. Twelve patients belonged to the idiopathic cardiomyopathy, 8 were related to alcoholism, 3 belonged to the familiar type, one case was a of post-partum cardiomyopathy and another of endomyocardial fibrosis. The selection was made taking into account the existence of heart failure, embolism or arrhythmia, in patient in which the common causes of heart disease were ruled out. A clinical, electrocardiographic and radiologic study was performed in every case. Some laboratory test were also done, including a serelogical one for Chagas' disease in 10 cases. Fourteen patients died and necropsy was carried out in each of them.  Findings related to...

Twentyfive patients with cardiomyopathy coming from different regions of Peru have been studied the majority (22) at the Hospital Dos de Mayo in the city of Lima. Twentythree were males and two females, and their ages were between 13 and 65 years. Twelve patients belonged to the idiopathic cardiomyopathy, 8 were related to alcoholism, 3 belonged to the familiar type, one case was a of post-partum cardiomyopathy and another of endomyocardial fibrosis. The selection was made taking into account the existence of heart failure, embolism or arrhythmia, in patient in which the common causes of heart disease were ruled out. A clinical, electrocardiographic and radiologic study was performed in every case. Some laboratory test were also done, including a serelogical one for Chagas' disease in 10 cases. Fourteen patients died and necropsy was carried out in each of them.  Findings related to...