The present quantitative, descriptive, correlational, cross-sectional investigation was carried out during 2020 with the purpose of determining the relationship between the level of knowledge and the degree of compliance with preventive measures for ventilator-associated pneumonia, in its different dimensions, in nurses of the critical care unit of the Hospital Belén de Trujillo. The sample universe consisted of 47 nurses to whom a questionnaire was applied to measure the level of knowledge and a checklist to identify the degree of compliance with preventive measures, to measure the relationship between both variables the statistical test of Kendall's tau c, reaching the following conclusions: 72.3% of nurses have an excellent level of knowledge about the preventive measures of pneumonia associated with mechanical ventilation, 27.7% have a regular level of knowledge. 76.6% of nurses hav...