Peru harbors an extraordinary Floristic wealth that man through its history took advantage of to meet his needs; ancestral ethnobotanical wisdom, taught initially by the "Hampicamayoc", "Oquetlupuc", "Sircac", and which, at present, persists through the "healers", " emollients " and "grandmothers"; but unfortunately it has been lost due to the lack of communication and registration. As described, the objective of this research was to determine the ethnomedicinal flora of the district of La Esperanza, Trujillo, La L ibertad. For this, 96 semi - structured interviews were applied to the buyers and sellers of medicinal plants ofthe most representative markets of the district in question; In parallel, collection, drying, assembly , and labeling of botanical specimens were carried out; then determine its taxonomic characteristics: family , scientific and common name; and ethnobotanicals: part...