A quasi-experimental study was carried out with the objective of determining the effect of a neuropsychological intervention program on academic skills in reading, writing and mathematics in a group of first grade girls and boys of primary school at the Cadena Las Playas educational institution. municipality of Apartadó, Antioquia, Colombia, aged between 5 and 6 years, belonging to a low socioeconomic condition. Two groups were formed, the experimental and the control, each with 19 students. Measurement tests in reading, writing and arithmetic were applied to each participant. Subsequently, a neuropsychological intervention program was applied to the experimental group for seven months, consisting of group training using the NeuronUP kids program. At the end, measurements were applied again in the academic skills of both groups.   At the pretest level, no significant differences were f...