Limited information on location-specific yield-limiting nutrients in Ethiopia hinders optimal wheat production and increases the costs associated with other nutrient applications, emphasizing the need for targeted nutrient management strategies. A field experiment was conducted on a farmer’s field in Mojana Wodera district, North Shewa zone, Ethiopia, to identify the most yield-limiting nutrients for wheat (Triticum aestivum L.) during the 2020/2021 cropping season. The treatments were NPKSZnB (All), All-B, All-Zn, All-S1 (10.5 kg.ha-1 S), All-K, All-P, All-N, recommended NP, recommended NP + S2 (30 kg.ha-1 S), and the control (no fertilizer). The experiment was laid out in a randomized complete block design, with three replications. R software was used to analyze the data. Results showed that the nutrient omission treatments affect yield. The highest grain yield (5080 kg ha-1) was ob...