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Status epilepticus in children is a neurologic emergency with significant morbidity and must be treated in a timely manner to avoid irreversible neuronal damage. Benzodiazepines are the first-line treatment, which in turn differ in some effects, which may lead us to choose one over the other based on their ability to stop seizures, their route of administration, as well as its adverse effects. The present research work is a single-center randomized controlled clinical trial that aims to determine the effectiveness of the use of intramuscular Midazolam compared with intravenous diazepam for the treatment of convulsive status epilepticus in patients admitted to the pediatric emergency department of the Trujillo Regional Teaching Hospital. between January and December 2020. The average time to seizure cessation and the adverse effects of each drug will be analyzed to establish its effective...
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The aim of this experimental study was to determine the in vitro effect of ethanolic extract of leaves and flowers Tropaeolum majus "Nasturtium" on Staphylococcus aureus methicillin resistant (MRSA) ATCC 25923. Susceptibility testing was performed using the disk diffusion method. MRSA strains were spreaded on Mueller Hinton agar; discs with different concentrations of the extract were set on the agar. The plates were incubated at 37 ° C; halos were measured after 18 hours; all disks had inhibition zone whose size increased in direct proportion to the relative concentrations used. Macrodilution method was also used with concentrations of 10.535, 52.675, 105.35, 158.025 and 210.7 ug / ml of the extract, to which was added MRSA inoculum. These were incubated at 37 ° C for 18 hours, then set on Mueller Hinton agar plates to determine colony forming units (CFU), which were counted 18 hours ...