Uterine leiomyosarcomas are rare malignant tumors that usually present with nonspecific symptoms. The diagnosis is usually incidental; especially in postmenopausal women who are surgically intervened by uterine leiomyomas. Its association with pregnancy is rare, and there are only twelve cases reported to date. We present a case of uterine leiomyosarcoma in a pregnant patient who underwent hysterectomy due to uterine atony.

Luteoma of pregnancy is an infrequent non-neoplastic pathology of the ovary. It is usually an incidental finding during the evaluation of a pregnant patient in the third trimester or during a cesarean section. Occasionally, it may raise suspicion of cancer, resulting in unnecessary surgical resection of the ovary. We present the case of a 34-year-old woman who was in her third pregnancy and during the cesarean section, a 9 cm tumor of the right ovary was incidentally found and resected. The histological study was compatible with luteoma of pregnancy.

Ectopic pregnancy in hysterectomized patients is an uncommon event and it is rarely considered in the differential diagnosis. We present the case of a 30-year-old patient with hysterectomy performed 6 years before who presented to the emergency service with a 3-day evolution of lower abdominal pain. Ultrasonography showed a gestational sac with embryo and the presence of free fluid in the Douglas sac. Histological examination of the surgical piece revealed chorionic villi and an embryo within the uterine tube.

El luteoma del embarazo es una patología no neoplásica del ovario, de incidencia poco frecuente. Suele presentarse como hallazgo incidental durante la evaluación de una paciente embarazada en el tercer trimestre o en el momento del acto quirúrgico de una cesárea. En ocasiones, puede llevar a sospechar una neoplasia maligna, derivando así en una resección quirúrgica innecesaria del ovario. Presentamos el caso de una mujer de 34 años que cursaba su tercera gestación y a quien, durante la cesárea, se le halló una tumoración ovárica derecha de 9 cm de diámetro que fue resecada. El estudio histológico fue compatible con luteoma del embarazo.

Los leiomiosarcomas uterinos son tumores malignos poco frecuentes que generalmente se presentan con síntomas inespecíficos, por lo que su diagnóstico suele ser incidental. Los casos más frecuentes se presentan en mujeres posmenopáusicas a quienes se les interviene quirúrgicamente por leiomiomas. La asociación de los leiomiosarcomas uterinos con la gestación es rara; solo existen doce casos reportados hasta la actualidad. Se presenta un caso de leiomiosarcoma uterino en una paciente gestante a quien se le realizó histerectomía por atonía uterina.

Introduction: A subgroup of breast carcinomas overexpress epidermal growth factor-2 (HER2). The determination of this overexpression is carried out by immunohistochemistry. The difficulty of diagnosis by this method arises when the result is ambiguous (2+), thus it is necessary to perform in situ hybridization (ISH) to determine the amplification of the HER2/neu gene. Objective: To determine if, in HER2 2+ cases, the amplification of the HER 2 / neu gene is associated with prognostic clinicopathological factors. Design: Observational, cross-sectional, descriptive study. Institution: Surgical pathology service, Guillermo Almenara Irigoyen Hospital. Lima, Peru. Participants: Cases of breast cancer HER2 2+. Methodology: We studied 117 cases of Her2 2+ breast cancer diagnosed between the years 2010 - 2015, to which ISH was subsequently performed. All the data were analyzed with the statistic...