The main objective of this study was to determine the antioxidant capacity and total phenol content of 50 medicinal plant species traditionally used as antidiabetic agents in the Loreto region. Antioxidant activity was evaluated by DPPH, ABTS and FRAP assays, and total phenol content was evaluated by Folin Ciocalteu method. The results showed that Euterpe oleracea was the species with the highest antioxidant capacity in all test. DPPH assays with a value of 5543.95 ± 178.32 µmol Trolox/g, ABTS with a value of 9775.27±5.08 µmol Trolox/g and FRAP with a value of 5725.12 ± 1.80 µmol Trolox/g. Likewise, Euterpe oleracea also presented the highest total phenol content with a value of 6376.02 ± 48.49 mg GAE/g, which evidenced a significant positive correlation between phenolic content and antioxidant capacity of the species studied. Petiveria alliacea and Urera baccifera were the specie...