Mucormycosis is a rare but fulminant invasive fungal infection caused by fungi of the order Mucorales. It primarily affects patients with risk factors such as diabetes mellitus, hematologic malignancies, solid organ or hematopoietic stem cell transplantation, and prolonged immunosuppressive therapy. Its various clinical forms include the rhino-cerebral presentation, one of the most aggressive, characterized by rapid local progression with involvement of orbital, neurological and vascular structures, and high lethality if not diagnosed and treated promptly. We present the case of a 53-year-old male patient with a history of poorly controlled type 2 diabetes mellitus, who sought medical attention due to severe headache, right periorbital edema, and diplopia that had been present for 72 hours. A computed tomography (CT) scan of the paranasal sinuses revealed occupation of the left sphenoid ...