Ionospheric irregularities are a common phenomenon in the low-latitude ionosphere. They can be seen in situ as depletions of plasma density, radar plasma plumes, or ionogram spread F by ionosondes. In this paper, we compared simultaneous observations of plasma plumes by the Jicamarca Unattended Long-term Investigations of the Ionosphere and Atmosphere (JULIA) radar, ionogram spread F generated from ionosonde observations installed at the Jicamarca Radio Observatory (JRO), and irregularities observed in situ by Swarm in order to determine whether Swarm in situ observations can be used as indicators of the presence of plasma plumes and spread F on the ground. The study covered the years from 2014 to 2018, as this was the period for which JULIA, Swarm, and ionosonde data sets were available. Overall, the results showed that Swarm's in situ density fluctuations on magnetic flux tubes passing...