Objective: To determine the surface roughness and color stability of a nanohybrid resin subjected to different salivary pH at different times. Materials and methods: experimental, comparative, in vitro study, in which 45 discs of EA2 nanohybrid resin (OPALLIS FGM) of 10 mm in diameter and 1 mm in thickness. They were randomly distributed in three groups (n = 15), each of the resin discs was subjected to an evaluation of its roughness by means of a digital roughness meter (TESTER SRT-6200) and color by colorimeter (Tooth Color Comparator). The discs according to their group were immersed in 18ml of artificial saliva modified with citric acid until obtaining saliva of pH 5, 6 and 7 respectively and placed in specific reservoirs maintained at 37 ° C, according to the specifications of the ANSI / ADA n0 standard. 66, after 168 and 504 hours of storage, a second and thir...