Propone determinar la asociación entre los índices neutrófilos/linfocitos y plaquetas/linfocitos y el diagnóstico de tiroiditis de Hashimoto en el Hospital Nacional Dos de Mayo. La recolección de información será a través de la ficha de datos de los pacientes con diagnóstico de tiroiditis de Hashimoto y grupo de sujetos sanos. También se evaluarán los valores de hormona estimulante del tiroides, T4 libre, proteína C reactiva, anticuerpos antiTPO, anticuerpos anti Tg y hemograma en cada grupo. El análisis estadístico será para las variables categóricas mediante la prueba de chi cuadrado, se informarán como números y porcentajes. Se utilizará la prueba de correlación de Pearson para evaluar la correlación entre las variables del estudio. Y el análisis de regresión logística considerando la edad y otras variables para observar si el NRL y PLR son marcadores independi...

Background: Lung cancer has highest mortality in both sexes. Current management of lung adenocarcinoma includes determining epidermal growth factor receptor (EGFR) mutational status as this is the target of erlotinib, a biologic therapy. Case report: A 62 yearold male with high smoking cancer risk presented chronic headache for a month, and magnetic resonance showed a brain tumor. Surgical specimen diagnosis was metastatic pulmonary adenocarcinoma by immunohistochemistry (TTF-1 (+)). An asymptomatic lesion in the right upper lobe of the lung was identified by tomography. Due to positivity to EGFR gene exon 21 mutation erlotinib was started; it was well tolerated by the patient. The patient died 31 months after diagnosis. Discussion: Treatment with erlotinib was initially indicated in the profile of an Asian and non-smoker woman patient. The overall survival rate with erlotinib in patient...

Diabetic hand syndrome is a rare and underdiagnosed complication of diabetes mellitus. This term is used to describe a potentially dangerous infection of the hand, characterized by debilitating musculoskeletal disorders. Although the diagnosis is commonly made in tropical regions, cases have also been reported in non-tropical and in marginal urban areas. The pathophysiology of this syndrome remains unclear because, unlike diabetic foot, peripheral neuropathy and vascular disease do not seem to a play major role. Evidence suggests that it may be associated with the duration of diabetes, poor metabolic control and microvascular complications. In this article, we present the cases of two patients with diabetic hand syndrome. The first case involves a 52-year-old female patient from a rural area, diagnosed with type 2 diabetes mellitus six years ago, currently in poor metabolic control. She ...