Objectives: To determine the incidence of neuropathic pain after endodontic treatment with follow-up at 6 months. Materials and Methods: This was a prospective observational clinical study that was carried out on patients who underwent endodontic treatment or retreatment carried out in the Master of Endodontics at the International University of Catalonia (UIC) from January 2022 to December 2022. After the treatment, a six-month follow-up was carried out, determining the presence of persistent pain, and whether the cause was of non-odontogenic origin, through anamnesis and physical examination carried out in the Department of Craniomandibular Dysfunction and Orofacial Pain of the Faculty of Dentistry. Results: A total of 231 treatments were obtained, obtaining a 53% response via telephone call. A descriptive analysis of the results was done, there were 88 patients who did not present pai...