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Oncological outcomes of laparoscopic radical hysterectomy versus radical abdominal hysterectomy in patients with early-stage cervical cancer: a multicenter analysis

Publicado por
Juliana, Rodriguez, Jose Alejandro, Rauh-Hain, James, Saenz, David, Ortiz Isla, Gabriel Jaime, Rendon Pereira, Diego, Odetto, Fabio, Martinelli, Vladimir, Villoslada Terrones, Ignacio, Zapardiel, Lina Maria, Trujillo, Milagros, Perez, Marcela, Hernandez, Jose, Martin Saadi, Francesco, Raspagliesi, Henry, Valdivia, Jaime, Siegrist, Shuangshuang, Fu, Mindy, Hernandez Nava, Lina, Echeverry, Florencia, NollAntonino Ditto, Aldo, Lopez Blanco, Alicia, Hernandez, Rene, Pareja

Publicado 2021

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Introduction: Recent evidence has shown adverse oncological outcomes when minimally invasive surgery is used in early-stage cervical cancer. The objective of this study was to compare disease-free survival in patients that had undergone radical hysterectomy and pelvic lymphadenectomy, either by laparoscopy or laparotomy. Methods: We performed a multicenter, retrospective cohort study of patients with cervical cancer stage IA1 with lymph-vascular invasion, IA2, and IB1 (FIGO 2009 classification), between January 1, 2006 to December 31, 2017, at seven cancer centers from six countries. We included squamous, adenocarcinoma, and adenosquamous histologies. We used an inverse probability of treatment weighting based on propensity score to construct a weighted cohort of women, including predictor variables selected a priori with the possibility of confounding the relationship between the surgic...