Expression of MMP-2, -8 and -9 in Inflamed Pulp

Descripción del Articulo

2010 IADR/PER General Session (Barcelona, Spain)
Detalles Bibliográficos
Autores: Pereira, J.C., Mattos, M.C., Hermoza Novoa, Monica, Mary Cestari, Tania, Granjeiro, Jose, Calabria, M.P.
Formato: objeto de conferencia
Fecha de Publicación:2010
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:español
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/668108
Enlace del recurso:http://hdl.handle.net/10757/668108
Nivel de acceso:acceso abierto
Materia:Inflamed Pulp
PE
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dc.title.es_PE.fl_str_mv Expression of MMP-2, -8 and -9 in Inflamed Pulp
title Expression of MMP-2, -8 and -9 in Inflamed Pulp
spellingShingle Expression of MMP-2, -8 and -9 in Inflamed Pulp
Pereira, J.C.
Inflamed Pulp
PE
title_short Expression of MMP-2, -8 and -9 in Inflamed Pulp
title_full Expression of MMP-2, -8 and -9 in Inflamed Pulp
title_fullStr Expression of MMP-2, -8 and -9 in Inflamed Pulp
title_full_unstemmed Expression of MMP-2, -8 and -9 in Inflamed Pulp
title_sort Expression of MMP-2, -8 and -9 in Inflamed Pulp
author Pereira, J.C.
author_facet Pereira, J.C.
Mattos, M.C.
Hermoza Novoa, Monica
Mary Cestari, Tania
Granjeiro, Jose
Calabria, M.P.
author_role author
author2 Mattos, M.C.
Hermoza Novoa, Monica
Mary Cestari, Tania
Granjeiro, Jose
Calabria, M.P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, J.C.
Mattos, M.C.
Hermoza Novoa, Monica
Mary Cestari, Tania
Granjeiro, Jose
Calabria, M.P.
dc.subject.es_PE.fl_str_mv Inflamed Pulp
topic Inflamed Pulp
PE
dc.subject.country.es_PE.fl_str_mv PE
description 2010 IADR/PER General Session (Barcelona, Spain)
publishDate 2010
dc.date.accessioned.none.fl_str_mv 2023-07-02T16:39:02Z
dc.date.available.none.fl_str_mv 2023-07-02T16:39:02Z
dc.date.issued.fl_str_mv 2010-07
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10757/668108
dc.identifier.isni.none.fl_str_mv 0000 0001 2196 144X
url http://hdl.handle.net/10757/668108
identifier_str_mv 0000 0001 2196 144X
dc.language.iso.es_PE.fl_str_mv spa
language spa
dc.relation.url.es_PE.fl_str_mv https://iadr.abstractarchives.com/home
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
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https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/2/license.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/1/Protecao_do_complexo_dentino_pulpar_Sayuri%20Tamara%20Trujil.pdf
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spelling b5b6ad9ca33388227a179aaf414054ac500fed94cc603618c8f4d91713d4ef0279d50072daea144b5841b1dee32010671cac9550009382e4f84407d0cb55250f903a9b539500a1948c670a14fc2b7dea3d8929291b38500c66ffe68630397bed1278bdb0748bfe6500Pereira, J.C.Mattos, M.C.Hermoza Novoa, MonicaMary Cestari, TaniaGranjeiro, JoseCalabria, M.P.2023-07-02T16:39:02Z2023-07-02T16:39:02Z2010-07http://hdl.handle.net/10757/6681080000 0001 2196 144X2010 IADR/PER General Session (Barcelona, Spain)Objective: to assess the presence of MMP-2, MMP-8 and MMP-9 in different stags of pulp inflammation. Null hypothesis: 1- the expression pattern of MMP-2, MMP-9 and MMP-8 does not change in respect to the stages of pulp inflammation; 2- there is no difference among MMP-2, MMP-9 and MMP-8 expression, considering the same period of pulp inflammation. Methods: Specimens were divided in groups according to criteria adopted of subjective and objective clinical diagnosis of pulp condition: GI- Control = healthy pulp (n=7); GII- Reversible Pulpitis (n=4); GIII– Pulpitis in transition stage (n=4); GIV- Irreversible Pulpitis/Necrosis (n=8). After extraction, teeth were cut below the cement-enamel junction, fixed with 10% formalin for 48h and washed in water (24h). Each tooth was 4µm thickness sectioned, adhered to silane coated glass slides and immunostained (IS). The following scores were used for MMPs IS semi-quantitative analysis: 0= absent; 1= mild; 2= moderate; 3= intense. Kruskal-Wallis nonparametric statistical test (p<0.05) was used for inter groups and intra groups comparison. Results: Inter groups: Odontoblast layer (OL): MMP-2: GI=GII=GIII, GIII=GIV, GI>GIV (p<0.01) and GII>GIV (p<0.05); MMP-9: GI=GII=GIV, GII=GIII and GIII>GI (p<0.01); MMP-8: GI=GII=GIII=GIV. Deep pulp (DP): MMP-2: GI=GII=GIII, GIII=GIV, GI>GIV (p<0.001) and GII>GIV (p<0.01); MMP-9: GI=GII=GIII, GIII=GIV, GIV>GI (p<0.001) e GIV>GII (p<0.01); MMP-8: GI=GII, GIII=GIV, GIII>GI (p<0.05), GIV>GI (p<0.01), GIII>GII (p<0,05) e GIV>GII (p<0.05). Intra groups: OL - GI: MMP-2>MMP9 (p<0.001), MMP-2=MMP-8 and MMP-9=MMP-8; GII: MMP-2>MMP-9 (p<0.01); MMP-2=MMP-8 and MMP-9=MMP-8; GIII and GIV: MMP-2=MMP-9=MMP-8. DP: GI and GII: MMP-2=MMP-9=MMP-8; GIII: MMP-9>MMP-2 (p<0.05), MMP-2=MMP-8 and MMP-9=MMP-8; GIV: MMP-9>MMP-2 (p<0.01), MMP-2=MMP-8 and MMP-9=MMP-8. Conclusions: The expression of MMP-2, MMP-9 and MMP-8 varied according to the stage of pulp inflamation, in bolth OL and DP. MMP-2 is heigher expressed in healthy pulp. The heighest MMP-9 expression is related to inflamed pulp. MMP-8 is present in bolth health and inflamed pulp.application/pdfspaUniversidad Peruana de Ciencias Aplicadas (UPC)https://iadr.abstractarchives.com/homeinfo:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCInflamed PulpPEExpression of MMP-2, -8 and -9 in Inflamed Pulpinfo:eu-repo/semantics/conferenceObject2023-07-02T16:39:03ZTHUMBNAILProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdf.jpgProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdf.jpgGenerated Thumbnailimage/jpeg68981https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/4/Protecao_do_complexo_dentino_pulpar_Sayuri%20Tamara%20Trujil.pdf.jpg887d2afab6d9626c93b14a4e04f6278aMD54falseTEXTProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdf.txtProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdf.txtExtracted texttext/plain19677https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/3/Protecao_do_complexo_dentino_pulpar_Sayuri%20Tamara%20Trujil.pdf.txtc9a82bb392a3532ee372de6c13e5b816MD53falseLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52falseORIGINALProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdfProtecao_do_complexo_dentino_pulpar_Sayuri Tamara Trujil.pdfapplication/pdf31695https://repositorioacademico.upc.edu.pe/bitstream/10757/668108/1/Protecao_do_complexo_dentino_pulpar_Sayuri%20Tamara%20Trujil.pdfbb148ba0ef66ded0d8b801f54c3b71daMD51true10757/668108oai:repositorioacademico.upc.edu.pe:10757/6681082023-07-03 03:13:04.335Repositorio académico upcupc@openrepository.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
score 13.754011
Expression of MMP-2, -8 and -9 in Inflamed Pulp
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