Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010

Descripción del Articulo

Article
Detalles Bibliográficos
Autores: Oré,Marianela, Sáenz, Eliana, Cabrera, Rufino, Sanchez, Juan F., De Los Santos, Maxy, Lucas, Carmen M., Núñez, Jorge, Edgel, Kimberly A., Sopan, Justino, Fernández, Jorge, Carnero, G, Andres M., Baldeviano, Christian, Arrasco, Juan C., Graf, Paul C. F., Lescano, Andres G.
Formato: artículo
Fecha de Publicación:2015
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/558294
Enlace del recurso:http://hdl.handle.net/10757/558294
Nivel de acceso:acceso abierto
Materia:Leishmaniasis
Peruvian Military Personnel
Training Activities
Peru
id UUPC_22bc593a21e5efcd8a8bbf36baf8e320
oai_identifier_str oai:repositorioacademico.upc.edu.pe:10757/558294
network_acronym_str UUPC
network_name_str UPC-Institucional
repository_id_str 2670
dc.title.es_PE.fl_str_mv Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
title Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
spellingShingle Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
Oré,Marianela
Leishmaniasis
Peruvian Military Personnel
Training Activities
Peru
title_short Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
title_full Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
title_fullStr Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
title_full_unstemmed Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
title_sort Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
author Oré,Marianela
author_facet Oré,Marianela
Sáenz, Eliana
Cabrera, Rufino
Sanchez, Juan F.
De Los Santos, Maxy
Lucas, Carmen M.
Núñez, Jorge
Edgel, Kimberly A.
Sopan, Justino
Fernández, Jorge
Carnero, G, Andres M.
Baldeviano, Christian
Arrasco, Juan C.
Graf, Paul C. F.
Lescano, Andres G.
author_role author
author2 Sáenz, Eliana
Cabrera, Rufino
Sanchez, Juan F.
De Los Santos, Maxy
Lucas, Carmen M.
Núñez, Jorge
Edgel, Kimberly A.
Sopan, Justino
Fernández, Jorge
Carnero, G, Andres M.
Baldeviano, Christian
Arrasco, Juan C.
Graf, Paul C. F.
Lescano, Andres G.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oré,Marianela
Sáenz, Eliana
Cabrera, Rufino
Sanchez, Juan F.
De Los Santos, Maxy
Lucas, Carmen M.
Núñez, Jorge
Edgel, Kimberly A.
Sopan, Justino
Fernández, Jorge
Carnero, G, Andres M.
Baldeviano, Christian
Arrasco, Juan C.
Graf, Paul C. F.
Lescano, Andres G.
dc.subject.es_PE.fl_str_mv Leishmaniasis
Peruvian Military Personnel
Training Activities
Peru
topic Leishmaniasis
Peruvian Military Personnel
Training Activities
Peru
description Article
publishDate 2015
dc.date.accessioned.es_PE.fl_str_mv 2015-06-20T14:33:03Z
dc.date.available.es_PE.fl_str_mv 2015-06-20T14:33:03Z
dc.date.issued.fl_str_mv 2015-06-20
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.issn.es_PE.fl_str_mv 0002-9637
dc.identifier.doi.es_PE.fl_str_mv 10.4269/ajtmh.15-0107
dc.identifier.uri.es_PE.fl_str_mv http://hdl.handle.net/10757/558294
dc.identifier.eissn.es_PE.fl_str_mv 1476-1645
dc.identifier.journal.es_PE.fl_str_mv American Journal of Tropical Medicine and Hygiene (ajtmh)
identifier_str_mv 0002-9637
10.4269/ajtmh.15-0107
1476-1645
American Journal of Tropical Medicine and Hygiene (ajtmh)
url http://hdl.handle.net/10757/558294
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.url.es_PE.fl_str_mv http://www.ajtmh.org/content/early/2015/06/11/ajtmh.15-0107.full.pdf+html
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv American Society of Tropical Medicine and Hygiene
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
bitstream.url.fl_str_mv https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/1/outbreakcutaneous.pdf
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/2/license_url
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/3/license_text
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/4/license_rdf
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/5/license.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/6/outbreakcutaneous.pdf.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/7/outbreakcutaneous.pdf.jpg
bitstream.checksum.fl_str_mv 412ad31b199756066ffb1f5da252906d
4afdbb8c545fd630ea7db775da747b2f
d41d8cd98f00b204e9800998ecf8427e
d41d8cd98f00b204e9800998ecf8427e
1ed8f33c5404431ad7aabc05080746c5
1fffa637891d7bb4f2985c76ca7e74ae
85d35fe51bc07011a7ec6fc84304e6aa
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio académico upc
repository.mail.fl_str_mv upc@openrepository.com
_version_ 1837187545069256704
spelling Oré,MarianelaSáenz, ElianaCabrera, RufinoSanchez, Juan F.De Los Santos, MaxyLucas, Carmen M.Núñez, JorgeEdgel, Kimberly A.Sopan, JustinoFernández, JorgeCarnero, G, Andres M.Baldeviano, ChristianArrasco, Juan C.Graf, Paul C. F.Lescano, Andres G.2015-06-20T14:33:03Z2015-06-20T14:33:03Z2015-06-200002-963710.4269/ajtmh.15-0107http://hdl.handle.net/10757/5582941476-1645American Journal of Tropical Medicine and Hygiene (ajtmh)ArticleMilitary personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2–36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.The outbreak response was supported by the Peruvian Army Health Command COSALE and the Peruvian Ministry of Health through the General Epidemiology Directorate and the Health Directorate II, south Lima, and the. In addition, partial support was provided by grants CO497_11_L1 and CO466_11_L1 of the Global Emerging Infections Surveillance and Response System (AFHSC/GEIS) of the U.S. Department of Defense and the training grant 2D43 TW007393 awarded to the U.S. Naval Medical Research Unit No. 6 (NAMRU-6) by the Fogarty International Center of the National Institutes of Health (FIC/NIH). This study is part of the dissertation of Marianela Ore for a Masters in Epidemiological Research offered jointly by the Universidad Peruana Cayetano Heredia (UPCH) and NAMRU-6.application/pdfengAmerican Society of Tropical Medicine and Hygienehttp://www.ajtmh.org/content/early/2015/06/11/ajtmh.15-0107.full.pdf+htmlinfo:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCLeishmaniasis31441bb7-5f9a-486c-8999-e769f343765c600Peruvian Military Personnelc588ac3a-ab70-4c25-967c-487bf1248c34600Training Activities094ed87b-dfe6-4a22-99c5-e43f26f123dd600Perud6e19394-1ad0-4de6-8bb9-5ec7e2e6d476600Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010info:eu-repo/semantics/articlemaryore05@yahoo.es2018-06-16T05:13:56ZMilitary personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2–36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.ORIGINALoutbreakcutaneous.pdfoutbreakcutaneous.pdfapplication/pdf943902https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/1/outbreakcutaneous.pdf412ad31b199756066ffb1f5da252906dMD51trueCC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52falselicense_textlicense_texttext/html; charset=utf-80https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53falselicense_rdflicense_rdfapplication/rdf+xml; charset=utf-80https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54falseLICENSElicense.txtlicense.txttext/plain; charset=utf-81659https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/5/license.txt1ed8f33c5404431ad7aabc05080746c5MD55falseTEXToutbreakcutaneous.pdf.txtoutbreakcutaneous.pdf.txtExtracted Texttext/plain44165https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/6/outbreakcutaneous.pdf.txt1fffa637891d7bb4f2985c76ca7e74aeMD56falseTHUMBNAILoutbreakcutaneous.pdf.jpgoutbreakcutaneous.pdf.jpgGenerated Thumbnailimage/jpeg103561https://repositorioacademico.upc.edu.pe/bitstream/10757/558294/7/outbreakcutaneous.pdf.jpg85d35fe51bc07011a7ec6fc84304e6aaMD57false10757/558294oai:repositorioacademico.upc.edu.pe:10757/5582942019-08-30 08:01:08.408Repositorio académico upcupc@openrepository.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
score 13.958958
Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares