Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru

• Autores: Carrillo-Ng, Hugo, Becerra-Goicochea, Lorena, Tarazona-Castro, Yordi, Pinillos-Vilca, Luis, Del Valle, Luis J., Aguilar-Luis, Miguel Angel, Tinco-Valdez, Carmen, Silva-Caso, Wilmer, Martins-Luna, Johanna, Peña-Tuesta, Isaac, Aquino-Ortega, Ronald, del Valle-Mendoza, Juana
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Universidad Peruana de Ciencias Aplicadas
• Repositorio: UPC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorioacademico.upc.edu.pe:10757/655810
• Enlace del recurso: http://hdl.handle.net/10757/655810
• Nivel de acceso: acceso abierto
• Materia: Cervical cancer; HPV; Human papillomavirus; Microbiota; PCR; Peru

Objective: To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results: A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).