Perfil clínico epidemiológico de drusas del nervio óptico en pacientes atendidos en el Instituto Regional de Oftalmología Javier Servat Univazo de Trujillo

• Autor: Aguilar Moscoso, Lucero Agustina
• Fecha de Publicación: 2019
• Institución: Universidad Nacional de Trujillo
• Repositorio: UNITRU-Tesis
• Lenguaje: español
• OAI Identifier: oai:dspace.unitru.edu.pe:20.500.14414/17844
• Enlace del recurso: https://hdl.handle.net/20.500.14414/17844
• Nivel de acceso: acceso abierto
• Materia: Drusas de nervio óptico; Defectos campimétricos; Espesor CFNR; Espesor capa de células ganglionares; Neuropatía óptica

To report the epidemiological clinical profile of optic nerve drusen (DNO) in patients treated at the Javier Servat Univazo IRO-JSU Regional Institute of Ophthalmology from January 2014 to December 2018 Methods: Descriptive and retrospective study, in which 250 clinical records of patients with a diagnosis of DNO in the IRO-JSU Neuro Ophthalmology service were reviewed in the period January 2014 to December 2018. 27 histories were selected that met the criteria of inclusion, taking as a sample a total of 46 eyes. Results: Of the 27 patients with DNO, 51.9% were in the age range between 30 and 59 years, 70.4% were women, 81.5% were of urban origin and 70.4% did not have comorbidities, being arterial hypertension the most frequent (11.1%). Of the total number of eyes, the bilateral involvement of DNO was 70.4%, the best corrected visual acuity (AVMC) of most eyes was between 20/20 to 20/30 (43.5%). In 52.2% they were asymptomatic, the most frequent clinical sign was an elevated papilla (69.6%). Regarding campimetric defects, 43.5% did not present any; while the most frequent defects were blind spot enlargement (17.4%), depression (13.04%) and contraction (10.87%). In the OCT analysis of the optic nerve, the thickness of the neuroretinal fiber layer (CFNR) and the thickness of the layer of ganglion cells were decreased in 60.9% and 54.4% of eyes, respectively. Optic neuropathy cases presented in 45.7%. In this group, 22.2% had no field defect and 22.2% had visual field depression, followed by 16.7% with an enlarged blind spot. CFNR and ganglion cell thickness decrease was found in 60% and 71% respectively. While the AVMC of 43% was found in the range between 20/20 to 20/30. There was no significant association between variables (p <0.05). Conclusions: The DNO are frequent in female sex, between 30 and 59 years old, of urban origin and without comorbidities. The majority are bilateral, asymptomatic, with an elevated papilla, AVMC in normal range, without campimetric defect in most, followed by an enlarged blind spot and depression; with decreased thickness of CFNR and ganglion cells; with frequent cases of associated optic neuropathy.