Actividad antiinflamatoria in vitro del extracto etanólico e hidroetanólico de hojas y tallo de Senna quinquangulata

• Autor: Uraco Mafaldo, Anthony Alejandro
• Formato: tesis de grado
• Fecha de Publicación: 2025
• Institución: Universidad Nacional De La Amazonía Peruana
• Repositorio: UNAPIquitos-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.unapiquitos.edu.pe:20.500.12737/11735
• Enlace del recurso: https://hdl.handle.net/20.500.12737/11735
• Nivel de acceso: acceso abierto
• Materia: Antiinflamatorios; Invitro; Extractos vegetales; Etáno; Extractos de hoja; Tallo; Senna quiquangulata; https://purl.org/pe-repo/ocde/ford#3.01.05; https://purl.org/pe-repo/ocde/ford#1.06.03

Senna quinquangulata is a plant preserved in the Loreto region, known for its extensive therapeutic properties in traditional medicine, including promising anti-inflammatory effects. Objective: To determine the anti-inflammatory activity of the ethanolic and hydroethanolic extracts of S. quinquangulata leaves and stems on plasma erythrocytes. Methodology: the leaves and stems were collected and used for the preparation of the alcoholic and hydroalcoholic extracts. The anti-inflammatory activity of these extracts was evaluated at concentrations of 10, 100, and 1000 µg/ml on plasma erythrocytes. Results: none of the evaluated concentrations of S. quinquangulata showed an inhibition rate greater than 50%, resulting in an IC50 > 1000 µg/mL. Conclusion: the tested extracts did not show anti inflammatory activity at the evaluated concentrations.