Un laboratorio de silicio: química sin reactivos

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The 2013 Nobel Prize in chemistry was awarded to A.Warshel, M.Levitt and M.Karplus for their contribution to the development of hybrid methods for computational chemistry. In this article a brief introduction about computational chemistry methods is presented. This paper will show the order in which...

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Detalles Bibliográficos
Autor: Benites Galbiati, Martín
Formato: artículo
Fecha de Publicación:2013
Institución:Pontificia Universidad Católica del Perú
Repositorio:PUCP-Institucional
Lenguaje:español
OAI Identifier:oai:repositorio.pucp.edu.pe:20.500.14657/99186
Enlace del recurso:http://revistas.pucp.edu.pe/index.php/quimica/article/view/8973/9381
Nivel de acceso:acceso abierto
Materia:Química Computacional
QM/MM
Premio Nobel
https://purl.org/pe-repo/ocde/ford#1.04.00
Descripción
Sumario:The 2013 Nobel Prize in chemistry was awarded to A.Warshel, M.Levitt and M.Karplus for their contribution to the development of hybrid methods for computational chemistry. In this article a brief introduction about computational chemistry methods is presented. This paper will show the order in which the QM/MM (Quantum Mechanics/Molecular Mechanics) methods were developed for the study of macromolecular systems and specially their application in enzymes and biochemistry. Finally, the reach and future prospects of these methods originally developed by A. Warshel, M.Levitt and M. Karplus in the seventies will be discussed.
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