Inmunidad poblacional contra el virus de la rabia en canes previo a la campaña de vacunación antirrábica en el distrito de Surquillo, Lima – Perú

• Autor: Chuquista Alcarraz, Olimpia
• Formato: tesis de maestría
• Fecha de Publicación: 2020
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: UPCH-Institucional
• Lenguaje: español
• OAI Identifier: oai:repositorio.upch.edu.pe:20.500.12866/9016
• Enlace del recurso: https://hdl.handle.net/20.500.12866/9016
• Nivel de acceso: acceso abierto
• Materia: Rabia; Inmunidad; Vacunación; Antirrábica; Canes; https://purl.org/pe-repo/ocde/ford#3.03.05; https://purl.org/pe-repo/ocde/ford#3.03.09; https://purl.org/pe-repo/ocde/ford#4.03.01

The objective of the study was to assess the susceptibility to infection by rabies virus of dogs in the district of Surquillo, prior to the execution of the national vaccination campaign. An observational cross-sectional and analytical study was designed, using the FAVN test as a laboratory method and a questionnaire to collect variables. Blood samples were collected from 141 dogs, that were at least3 months old, either male or female and were apparently healthy. They were classified into two groups: dogs that had not previously received rabies vaccination (30) and those that had a vaccination record (111). Of the total vaccinated dogs, 73.9% (82) exceeded the seroconversion limit, being protected according to the WHO (0.5UI / ml). Dogs that were one-year-old (p = 0.028) and those that had not received vaccination within the last three years (p = 0.05) were more receptive to the virus. In addition to the dogs vaccinated in the canine rabies vaccination campaign (p = 0.005), with monovalent vaccines (p = 0.005) within the last three years were the least receptive. With these results we can conclude that seroconversion was low, making the district vulnerable to face control of the spread of rabies virus entering the study area, especially in the population younger than one year of age and those who were not vaccinated within the previous 3 years: which can be considered as a criterion for selective vaccination in future rabies immunization campaigns.