Acute encephalitis associated with SARS-CoV-2: first case report in Peru

Descripción del Articulo

In the context of the COVID-19 pandemic, atypical clinical forms have been described, in which extra-respiratory symptoms predominate; among them, cases of concurrent neurological manifestations have been reported. Based on the coronavirus identification in the central nervous system in the 2002 SAR...

Descripción completa

Detalles Bibliográficos
Autores: Barreto-Acevedo, Elliot, Mariños, Evelyn, Espino, Poul, Troncoso, Jhonatan, Urbina, Luis, Valer, Nashely
Formato: artículo
Fecha de Publicación:2020
Institución:Universidad Peruana Cayetano Heredia
Repositorio:Revistas - Universidad Peruana Cayetano Heredia
Lenguaje:español
OAI Identifier:oai:revistas.upch.edu.pe:article/3754
Enlace del recurso:https://revistas.upch.edu.pe/index.php/RNP/article/view/3754
Nivel de acceso:acceso abierto
Materia:encephalitis; COVID-19; Peru
encefalitis; COVID-19; Perú
id REVUPCH_718825ae3a97ce1aca99ad3d5f5bf6ff
oai_identifier_str oai:revistas.upch.edu.pe:article/3754
network_acronym_str REVUPCH
network_name_str Revistas - Universidad Peruana Cayetano Heredia
repository_id_str
spelling Acute encephalitis associated with SARS-CoV-2: first case report in PeruEncefalitis aguda en pacientes COVID-19: primer reporte de casos en Perú.Barreto-Acevedo, ElliotMariños, EvelynEspino, PoulTroncoso, JhonatanUrbina, LuisValer, Nashelyencephalitis; COVID-19; Peruencefalitis; COVID-19; PerúIn the context of the COVID-19 pandemic, atypical clinical forms have been described, in which extra-respiratory symptoms predominate; among them, cases of concurrent neurological manifestations have been reported. Based on the coronavirus identification in the central nervous system in the 2002 SARS-CoV outbreak, a potential neurotropism of SARS-CoV-2 has been raised. Few patients with acute encephalitis associated with SARS-CoV-2 have been described in the world literature. In this report we present two cases of Peruvian patients with acute encephalitis concurrent to COVID-19, we reviewed the literature and discussed the possible mechanisms of neurotropism and neuroinvasion.En el contexto de la pandemia de COVID-19, se han descrito formas clínicas atípicas, en las que predominan síntomas extrar-respiratorios; entre ellos han sido reportados casos de manifestaciones neurológicas concurrentes. En base a la identificación de coronavirus en el sistema nervioso central en el brote SARS-CoV del 2002, se ha planteado un potencial neurotropismo del SARS-CoV-2. En la literatura mundial se han descrito escasos pacientes con encefalitis aguda asociada a SARS-CoV-2. En este reporte les presentamos dos casos de pacientes peruanos con encefalitis aguda concurrente a COVID-19, revisamos la literatura y discutimos los posibles mecanismos de neurotropismo y neuro-invasión.Universidad Peruana Cayetano Heredia2020-07-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.upch.edu.pe/index.php/RNP/article/view/375410.20453/rnp.v83i2.3754Revista de Neuro-Psiquiatria; Vol. 83 No. 2 (2020): April - June; 116-122Revista de Neuro-Psiquiatría; Vol. 83 Núm. 2 (2020): Abril - Junio; 116-122Revista de Neuro-Psiquiatria; v. 83 n. 2 (2020): Abril - Junio; 116-1221609-73940034-8597reponame:Revistas - Universidad Peruana Cayetano Herediainstname:Universidad Peruana Cayetano Herediainstacron:UPCHspahttps://revistas.upch.edu.pe/index.php/RNP/article/view/3754/4183info:eu-repo/semantics/openAccessoai:revistas.upch.edu.pe:article/37542020-07-15T22:39:47Z
dc.title.none.fl_str_mv Acute encephalitis associated with SARS-CoV-2: first case report in Peru
Encefalitis aguda en pacientes COVID-19: primer reporte de casos en Perú.
title Acute encephalitis associated with SARS-CoV-2: first case report in Peru
spellingShingle Acute encephalitis associated with SARS-CoV-2: first case report in Peru
Barreto-Acevedo, Elliot
encephalitis; COVID-19; Peru
encefalitis; COVID-19; Perú
title_short Acute encephalitis associated with SARS-CoV-2: first case report in Peru
title_full Acute encephalitis associated with SARS-CoV-2: first case report in Peru
title_fullStr Acute encephalitis associated with SARS-CoV-2: first case report in Peru
title_full_unstemmed Acute encephalitis associated with SARS-CoV-2: first case report in Peru
title_sort Acute encephalitis associated with SARS-CoV-2: first case report in Peru
dc.creator.none.fl_str_mv Barreto-Acevedo, Elliot
Mariños, Evelyn
Espino, Poul
Troncoso, Jhonatan
Urbina, Luis
Valer, Nashely
author Barreto-Acevedo, Elliot
author_facet Barreto-Acevedo, Elliot
Mariños, Evelyn
Espino, Poul
Troncoso, Jhonatan
Urbina, Luis
Valer, Nashely
author_role author
author2 Mariños, Evelyn
Espino, Poul
Troncoso, Jhonatan
Urbina, Luis
Valer, Nashely
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv encephalitis; COVID-19; Peru
encefalitis; COVID-19; Perú
topic encephalitis; COVID-19; Peru
encefalitis; COVID-19; Perú
description In the context of the COVID-19 pandemic, atypical clinical forms have been described, in which extra-respiratory symptoms predominate; among them, cases of concurrent neurological manifestations have been reported. Based on the coronavirus identification in the central nervous system in the 2002 SARS-CoV outbreak, a potential neurotropism of SARS-CoV-2 has been raised. Few patients with acute encephalitis associated with SARS-CoV-2 have been described in the world literature. In this report we present two cases of Peruvian patients with acute encephalitis concurrent to COVID-19, we reviewed the literature and discussed the possible mechanisms of neurotropism and neuroinvasion.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistas.upch.edu.pe/index.php/RNP/article/view/3754
10.20453/rnp.v83i2.3754
url https://revistas.upch.edu.pe/index.php/RNP/article/view/3754
identifier_str_mv 10.20453/rnp.v83i2.3754
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.upch.edu.pe/index.php/RNP/article/view/3754/4183
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Peruana Cayetano Heredia
publisher.none.fl_str_mv Universidad Peruana Cayetano Heredia
dc.source.none.fl_str_mv Revista de Neuro-Psiquiatria; Vol. 83 No. 2 (2020): April - June; 116-122
Revista de Neuro-Psiquiatría; Vol. 83 Núm. 2 (2020): Abril - Junio; 116-122
Revista de Neuro-Psiquiatria; v. 83 n. 2 (2020): Abril - Junio; 116-122
1609-7394
0034-8597
reponame:Revistas - Universidad Peruana Cayetano Heredia
instname:Universidad Peruana Cayetano Heredia
instacron:UPCH
instname_str Universidad Peruana Cayetano Heredia
instacron_str UPCH
institution UPCH
reponame_str Revistas - Universidad Peruana Cayetano Heredia
collection Revistas - Universidad Peruana Cayetano Heredia
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1846152848862085120
score 12.884314
Acute encephalitis associated with SARS-CoV-2: first case report in Peru
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares