Thymic hypoplasia in pediatric patients with respiratory illnesses

• Autores: Fundora-Hernández, Hermes, Tamayo-Gutiérrez, Sandier, Rabaza-Pérez, Jesús, Rodríguez-Gutiérrez, Katia, Antiguas-Valdés, Evelyn Milagros, Ricardo-Pereira, Hermidia
• Formato: artículo
• Fecha de Publicación: 2023
• Institución: Universidad Peruana Cayetano Heredia
• Repositorio: Revistas - Universidad Peruana Cayetano Heredia
• Lenguaje: español
• OAI Identifier: oai:revistas.upch.edu.pe:article/4548
• Enlace del recurso: https://revistas.upch.edu.pe/index.php/RMH/article/view/4548
• Nivel de acceso: acceso abierto
• Materia: Ultrasonografía; timo; sistema respiratorio; enfermedad respiratoria; ultrasonography; thymus; respiratory system; respiratory disease

Objective: To determine the clinical and epidemiologic features of children with thymic hypoplasia and respiratory illnesses in Cuba. Methods: A retrospective study was conducted among children of 1-6 years of age of both sexes attended at a Pediatric Immunology Program of Hospital Materno Infantil Ángel Arturo Aballí Arellano in Habana, Cuba from September 2019 to August 2022. Children with thymic hypoplasia with and without a history of a respiratory illness either infectious or non-infectious were included.Results: No association between age andsex with thymic hypoplasia but an association was found with children with a severe respiratory illness. Factors associated with a severe respiratory illness were ineffective breastfeeding, history of an atopic condition, pregnancy of high risk, prematurity and exposure to tobacco smoke. Conclusions:Thymic hypoplasia was not associated with age or sex. An association with mild-moderate thymic hypoplasia was found with a severe respiratory illness.