Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration

Descripción del Articulo

We present the case of a 38 year-old male, farmer, born in Lamas, San Martin (Peruvian jungle), who for the past 8 months suffered of diarrhea, intermittent fever, abdominal pain, weight loss and severe anemia. On admission the patient was lucid and exhibited malaise, pallor and generalized lymphade...

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Detalles Bibliográficos
Autores: Carballo, Fernando, López, Rubén, Mechán, Victor, Vilchez, Luis
Formato: artículo
Fecha de Publicación:2011
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:ojs.csi.unmsm:article/995
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/995
Nivel de acceso:acceso abierto
Materia:Hodgkin lymphoma with lymphocytic depletion
lymphoproliferative syndrome
Reed Sternberg cells
EBV Epstein-Barr virus.
Linfoma de Hodgkin con depleción linfocítica
síndrome linfoproliferativo
células de Reed Sternberg
EBV-virus de Epstein Barr.
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spelling Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltrationLinfoma de Hodgkin con depleción linfocítica e infiltración difusa de médula óseaCarballo, FernandoLópez, RubénMechán, VictorVilchez, LuisHodgkin lymphoma with lymphocytic depletionlymphoproliferative syndromeReed Sternberg cellsEBV Epstein-Barr virus.Linfoma de Hodgkin con depleción linfocíticasíndrome linfoproliferativocélulas de Reed SternbergEBV-virus de Epstein Barr.We present the case of a 38 year-old male, farmer, born in Lamas, San Martin (Peruvian jungle), who for the past 8 months suffered of diarrhea, intermittent fever, abdominal pain, weight loss and severe anemia. On admission the patient was lucid and exhibited malaise, pallor and generalized lymphadenopathy (size less than 0.5 cm) hepatosplenomegaly and abdominal displaceable dullness. Abdominal computed tomography showed hepatosplenomegaly and retroperitoneal, mesenteric and other adenopathies. Node biopsy revealed Reed-Sternberg cells, mononuclear cells, eosinophiles and scarce lymphocytes. Immunohistochemical node staining was positive for CD15 and CD30 antibodies. Bone biopsy showed diffuse fibrosis, mononuclear cells and scarcity of lymphocytes. In situ hybridization for EBV Epstein Barr virus was positive in neoplastic cells.desde hacía 8 meses presentaba diarreas, fiebre intermitente, dolor abdominal, pérdida ponderal y anemia severa. Aunque lúcido, a su ingreso el paciente exhibía mal estado general, palidez y adenopatías generalizadas de menos de 0,5 cm, hepatoesplenomegalia y matidez desplazable. La tomografía computarizada abdominal reveló hepatoesplenomegalia y múltiples adenopatías retroperitoneales, mesentéricas y otras. La biopsia de ganglio mostró células de Reed Sternberg, células mononucleares, eosinófilos y escasos linfocitos. La inmunohistoquímica ganglionar fue positiva para anticuerpos CD15 y CD30. La biopsia de hueso señaló fibrosis difusa, células mononucleares y marcada escasez de linfocitos. La hibridización in situ para EBV-virus de Epstein Barr fue positiva en las células neoplásicas.Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana2011-06-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/99510.15381/anales.v72i2.995Anales de la Facultad de Medicina; Vol. 72 No. 2 (2011); 137-140Anales de la Facultad de Medicina; Vol. 72 Núm. 2 (2011); 137-1401609-94191025-5583reponame:Revistas - Universidad Nacional Mayor de San Marcosinstname:Universidad Nacional Mayor de San Marcosinstacron:UNMSMspahttps://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/995/818Derechos de autor 2011 Fernando Carballo, Rubén López, Victor Mechán, Luis Vilchezhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessoai:ojs.csi.unmsm:article/9952020-04-15T19:18:25Z
dc.title.none.fl_str_mv Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
Linfoma de Hodgkin con depleción linfocítica e infiltración difusa de médula ósea
title Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
spellingShingle Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
Carballo, Fernando
Hodgkin lymphoma with lymphocytic depletion
lymphoproliferative syndrome
Reed Sternberg cells
EBV Epstein-Barr virus.
Linfoma de Hodgkin con depleción linfocítica
síndrome linfoproliferativo
células de Reed Sternberg
EBV-virus de Epstein Barr.
title_short Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
title_full Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
title_fullStr Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
title_full_unstemmed Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
title_sort Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
dc.creator.none.fl_str_mv Carballo, Fernando
López, Rubén
Mechán, Victor
Vilchez, Luis
author Carballo, Fernando
author_facet Carballo, Fernando
López, Rubén
Mechán, Victor
Vilchez, Luis
author_role author
author2 López, Rubén
Mechán, Victor
Vilchez, Luis
author2_role author
author
author
dc.subject.none.fl_str_mv Hodgkin lymphoma with lymphocytic depletion
lymphoproliferative syndrome
Reed Sternberg cells
EBV Epstein-Barr virus.
Linfoma de Hodgkin con depleción linfocítica
síndrome linfoproliferativo
células de Reed Sternberg
EBV-virus de Epstein Barr.
topic Hodgkin lymphoma with lymphocytic depletion
lymphoproliferative syndrome
Reed Sternberg cells
EBV Epstein-Barr virus.
Linfoma de Hodgkin con depleción linfocítica
síndrome linfoproliferativo
células de Reed Sternberg
EBV-virus de Epstein Barr.
description We present the case of a 38 year-old male, farmer, born in Lamas, San Martin (Peruvian jungle), who for the past 8 months suffered of diarrhea, intermittent fever, abdominal pain, weight loss and severe anemia. On admission the patient was lucid and exhibited malaise, pallor and generalized lymphadenopathy (size less than 0.5 cm) hepatosplenomegaly and abdominal displaceable dullness. Abdominal computed tomography showed hepatosplenomegaly and retroperitoneal, mesenteric and other adenopathies. Node biopsy revealed Reed-Sternberg cells, mononuclear cells, eosinophiles and scarce lymphocytes. Immunohistochemical node staining was positive for CD15 and CD30 antibodies. Bone biopsy showed diffuse fibrosis, mononuclear cells and scarcity of lymphocytes. In situ hybridization for EBV Epstein Barr virus was positive in neoplastic cells.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-13
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/995
10.15381/anales.v72i2.995
url https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/995
identifier_str_mv 10.15381/anales.v72i2.995
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/995/818
dc.rights.none.fl_str_mv Derechos de autor 2011 Fernando Carballo, Rubén López, Victor Mechán, Luis Vilchez
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2011 Fernando Carballo, Rubén López, Victor Mechán, Luis Vilchez
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana
dc.source.none.fl_str_mv Anales de la Facultad de Medicina; Vol. 72 No. 2 (2011); 137-140
Anales de la Facultad de Medicina; Vol. 72 Núm. 2 (2011); 137-140
1609-9419
1025-5583
reponame:Revistas - Universidad Nacional Mayor de San Marcos
instname:Universidad Nacional Mayor de San Marcos
instacron:UNMSM
instname_str Universidad Nacional Mayor de San Marcos
instacron_str UNMSM
institution UNMSM
reponame_str Revistas - Universidad Nacional Mayor de San Marcos
collection Revistas - Universidad Nacional Mayor de San Marcos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 13.947374
Hodgkin’s lymphoma with lymphocyte depletion and diffuse bone marrow infiltration
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