Fatal encephalitis caused by free-living amoebas in an infant from Piura, Peru

Descripción del Articulo

Free-living amoeba encephalitis usually causes severe disease with high mortality despite appropriate management. We present the case of a 7-month-old infant from northern Peru who had a 10-day illness characterized by irritability, hypoactivity, gaze deviation, and drowsiness. Both cerebrospinal fl...

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Detalles Bibliográficos
Autores: Mori-Llontop, Laura Melissa, Alaña-Peña, Verónica María, Pregúntegui-Loayza, Ivethe F., Mayo-Simón, Nancy Lourdes, Cabello-Vílchez, Alfonso Martin, López-Revilla, José
Formato: artículo
Fecha de Publicación:2025
Institución:Universidad Nacional Mayor de San Marcos
Repositorio:Revistas - Universidad Nacional Mayor de San Marcos
Lenguaje:español
OAI Identifier:oai:revistasinvestigacion.unmsm.edu.pe:article/30324
Enlace del recurso:https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/30324
Nivel de acceso:acceso abierto
Materia:Amoeba
Mortalidad
Lactante
Encefalitis
Perú
Mortality
Infant
Encephalitis
Peru
Descripción
Sumario:Free-living amoeba encephalitis usually causes severe disease with high mortality despite appropriate management. We present the case of a 7-month-old infant from northern Peru who had a 10-day illness characterized by irritability, hypoactivity, gaze deviation, and drowsiness. Both cerebrospinal fluid analysis and brain biopsy revealed structures compatible with free-living amoebae. Molecular analysis by PCR was ultimately negative for Acanthoameba sp. and Ballamuthia sp. Molecular analysis of CSF is important to identify the amoeba species involved.
Fatal encephalitis caused by free-living amoebas in an infant from Piura, Peru
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