Actividad antimicótica in vitro y elucidación estructural del aceite esencial de las hojas de Minthostachys mollis "Muña"

• Autores: Cano Pérez, Carlos, Bonilla Rivera, Pablo, Roque A., Mirtha, Ruiz Quiroz, Julio
• Formato: artículo
• Fecha de Publicación: 2006
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/5075
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/5075
• Nivel de acceso: acceso abierto
• Materia: Minthostachys mollis; essential oil; antimycotic activity; gas chromatography; monoterpenes; aceite esencial; actividad antimicótica; cromatografía de gases; monoterpenos

The objective of this paper is ta demonstrate the in vitro antimycotic activity and elucidation of sorne metabolites of the essentiaI oil of Minthostachys mollis (muña) that comes from the district of Huacrapuquio (2700m. altitude) in the province of Tarma. The essential oil of the leaves of Minthostachys mollis (muña) has been extracted by hydrodistillation method. This was subjected to Physical-Chemical analysis, Gas Chromatography (CC) to determine the chemical compasitian and then determining that fungicidal and fungistatic activity to be due to the following Monoterpenes: Pulegone, Limoneno, Menthone and also Myrcene. The antimycotic activity for Candida albicans was determined by the Agar-well diffusion assay and the method of dilution in tubes, the inhibition of growth of Trichophytun tonsurans, Trichophytun mentagophytus, Microsporun canis. For the diffusion in Agar test the diameters were as follows 30 mm for the 100% concentration of the essential muña oil and 35 mm for the 50% concentration of the same oil. The essential oil of muña inhibited growth of Trichophytun tonsurans, Trichophytun mentagophtus, Microsporun canis, probably by monoterpenes pharmacological action.