Magnesium levels in AIDS-associated tuberculosis or cryptococcosis patients, and relationship with treatment response

• Autores: Ronceros, Gerardo, Huaroto, Luz, Alvarado Ortíz, Carlos
• Formato: artículo
• Fecha de Publicación: 2002
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/1489
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1489
• Nivel de acceso: acceso abierto
• Materia: Magnesio; síndrome de inmunodeficiencia adquirida; tuberculosis; criptococosis; deficiencia de magnesio; Magnesium; acquired immunodeficiency syndrome; cryptococcosis; magnesium deficiency

OBJECTIVE: To demostrate that human immunodeficiency virus (HIV) patients in acquired immunodeficiency syndrome (AIDS) phase associated with tuberculosis (TB) or cryptococcosis have hypomagnesemia-related inadequate treatment response. DESIGN: Prospective and longitudinal study. MATERIALS AND METHODS: We studied 300 subjects, divided in six groups of 50 patients each: positive HIV patients, TB patients, AIDS patients with TB, AIDS patients with cryptococcosis, no-AIDS patients with acute infections and a normal group (blood donors). RESULTS: Average magnesium values were below normal in the groups AIDS/TB, AIDS/cryptococcosis and TB. There were important statistical differences in magnesium levels in the groups HIV, AIDS/TB, AIDS/ cryptococcosis and TB. With respect to hypomagnesemia, the group with less response to treatment was the AIDS+TB (27%). CONCLUSIONS: Hypomagnesemia is prevalent in chronic infectious diseases with important differences in magnesium levels among the four groups studied and AIDS/TB group showing more abnormalities.